产品货号：
Z19122
中文名称：
ITCH抗体
英文名称：
Anti-ITCH Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ITCH Antibody |
| 指标别名 | AIF4;AIP4;ITCH;NAPP1;NFE2 associated polypeptide 1 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB |
| 基因名称 | ITCH |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | ITCH antibody was raised against a 15 amino acid peptide near the amino terminus of human ITCH.The immunogen is located within amino acids 40 - 90 of ITCH. |
| 计算分子量 | 103kDa |
| 成分 | ITCH antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | ITCH antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | The Itchy E3 ubiquitin protein ligase (ITCH) is a member of the Nedd4 family of HECT domain E3 ubiquitin ligases (1).HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates,thus targeting specific proteins for lysosomal degradation.ITCH plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses (2).In B cells,ITCH is thought to associate with latent membrane protein 2A (LMP2A) of Epstein-Barr virus,specifically down-regulating its activity in B cell signaling (3).Mutations in this gene are a cause of syndromic multisystem autoimmune disease (4). |
| Uniprot ID | Q96J02 |
| 基因名全称 | Itchy E3 ubiquitin protein ligase |
| 蛋白名全称 | Itchy E3 ubiquitin protein ligase |
| 推荐稀释比 | ITCH antibody can be used for detection of ITCH by Western blot at 1 ～ 2μg/mL.Antibody validated:Western Blot in mouse samples.All other applications and species not yet tested. |
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